The research about vitamin D continues to impress us the importance of regular sun exposure as an ideal way to optimize the levels of vitamin D. The winter limits the exposure to sun and during those times, the best bet would be UVB light, because UV rays appear to have health benefits in the vitamin D production. One of the damaging tanning bed elements are the magnetic ballasts. The electric ballast is far less damaging which provide the lot of the danger from the tanning beds.
The benefits of the UVB exposure from the artificial light or the sun include but aren’t limited to the nitric oxide production, which lowers the blood pressure. Even it is named vitamin, it isn’t vitamin. It is potent neuro-regulatory steroidal hormone.
Correcting the deficiency of vitamin D may reduce the risk of dying by 50 percent, according to an analysis.
Vitamin D regulates the ability to fight chronic inflammation and infections. It produces two-hundred antimicrobial peptides like cathelicidin which is broad-spectrum antibiotic.
Many researches have shown has numerous benefits over the mental and physical health. One research has shown that it improves bacterial and viral infections, Alzheimer’s, autism and other brain dysfunction, stroke and heart disease, diabetes (type 1 and 2) and pregnancy outcomes.
Recent published studies demonstrate that boosted levels of vitamin D can improve pain in diabetics, depression, breast cancer and Crohn’s disease.
- Correcting the levels of vitamin D can improve the symptoms of Crohn’s disease. The serum Vitamin D levels are found to be lower in Crohn’s disease patients. Two of the seven DNA sequence variations showed association with the levels of vitamin D in those with Crohn’s disease, and the other four are associated with levels of vitamin D among controls.
Vitamin D Beneficially Affects Gene Activity
Vitamin D up-regulates body`s ability to combat chronic inflammation and infections. It is also responsible for the production of more than 200 anti-microbial peptides, out of which cathelicidin is the most important.
This is one of the reasons why vitamin D is effective against influenza and colds. According to a 2013 press release by Orthomolecular Medicine, vitamin D provides remarkable benefits to both physical and mental health, including the following:
– Autism, Alzheimer’s, and other brain dysfunction
– Bacterial and viral infections
– Pregnancy outcomes (reduced risk of Cesarean section and pre-eclampsia)
– Type 1 and 2 diabetes
– Heart disease and stroke
Relevance of Vitamin D in Crohn’s Disease
Earlier research linked low vitamin D levels with an increased risk of Chron`s disease and shown that fixing vitamin D deficiency improves symptoms of the disease, recent study found “significant interaction between vitamin D levels and Crohn’s disease susceptibility, as well as a significant association between vitamin D levels and genotype.”
Patients with Chron`s disease have been found to have low serum vitamin D levels. The researchers examined seven DNA sequence variations and two of them showed a notable associated with vitamin D levels in patients with Chron`s disease and four of them were associated with vitamin D levels among controls.
Vitamin D May Reduce Depression and Pain
- The Vitamin D supplementation can reduce the pain and depression in diabetic women. In a study, 61% of women reported neuropathic pain, burning or shooting pain in the feet and legs and 74 percent had sensory pain like tingling in the legs, fingers and hands and numbness.
The participants took 50000 IU of supplement (vitamin D2) every week for six months. At the end, the levels of depression had improved following the supplementation.
- The supplementation is a promising treatment for depression and pain in diabetes (type2), according to Todd Doyle (Ph.D.), the lead researcher. According to him, it is better to take D, than D2, as D2 can cause harm in long term usage.
There was analysis of fifty controlled trials with 94,000 participants that have shown 6 percent risk reduction in those who used vitamin D 3 and 2% risk increase in those who used D 2.
Why I Recommend Vitamin D3 Over D2
Drisdol is a synthetic form of vitamin D2—made by irradiating fungus and plant matter—and is the form of vitamin D typically prescribed by doctors. This is not the type produced by your body in response to sun or safe tanning bed exposure, which is vitamin D3.
According to a 2012 meta-analysis by the Cochrane Database,5 which assessed mortality rates for people who supplemented their diets with D2 versus those who did so with D3, there are significant differences in outcome between the two. The analysis of 50 randomized controlled trials, which included a total of 94,000 participants, showed:
– A six percent relative risk reduction among those who used vitamin D3
– A two percent relative risk increase among those who used D2
That said, the featured research certainly sheds light on the role vitamin D can play in the management of type 2 diabetes and associated side effects. And when you consider that an estimated 60 percent of type 2 diabetics are vitamin D deficient,6 there’s certainly plenty of room for improvement.
Additional support for the theory that vitamin D can be beneficial in the fight against type 2 diabetes was published in last year. Here, the researchers found “a strong additive interaction between abdominal obesity and insufficient 25(OH)D in regard to insulin resistance.” They also claim 47 percent of the increased odds of insulin resistance can be explained by the interaction between insufficient vitamin D levels and a high body mass index (BMI).
Yet another study published in Diabetes Care also suggests vitamin D supplements may help prevent type 2 diabetes mellitus in people with pre-diabetes. While the study is only an observational one and cannot establish causality, the researchers report that the participants who had the highest vitamin D levels were 30 percent less likely to develop diabetes during the three-year evaluation period, compared to those with the lowest levels.
Cut Your Breast Cancer Risk with Vitamin D, Cancer Surgeon Suggests
Professor Kefah Mokbel, a British breast cancer surgeon, supplementation with vitamin D helps cut breast cancer risk. According to the article,
“Prof. Mokbel has also requested Jeremy Hunt, the Health Secretary, to make [vitamin D] pills freely available as this would result in saving about a 1,000 lives annually. ‘I am calling for all women from the age of 20 to be given free vitamin D supplements on the NHS because it is effective in protecting against breast cancer,’ Prof. Mokbel said.
…[R]esearch10, 11 conducted by the Creighton University School of Medicine in Omaha, Neb, which analyzed menopausal women from rural eastern Nebraska for over four years, revealed that taking vitamin D supplements along with calcium cut about 60 percent risk of cancer, including breast, lung and colon cancer…’It’s inexpensive, it’s safe, and it’s easy to take. It’s something that should be considered by a lot of people,’ says Joan Lappe, professor of nursing and medicine at Creighton University School of Medicine in Omaha, Neb. ‘It’s low-risk with maybe a high pay-off.’”
Vitamin D Is Critical for Cancer Prevention
Mounting evidence shows that vitamin D has enormous protective effect against various cancer types, including lung, ovarian, breast, prostate, pancreatic, and skin cancers. This information stems from over 2,500 laboratory trials as well as 200 epidemiological studies.
For instance, according to a 2007 study published in the American Journal of Preventive Medicine, a serum 25(OH)D level of more than 33 ng/mL was linked to 50 % lower risk of colorectal cancer. Additionally, a research reported by the International Journal of Cancer found out that a 10 ng/ml increase in serum vitamin D levels was associated with a 15 % reduction in colorectal cancer incidence and 11 % reduction in breast cancer incidence.
Most Important—Maintaining Optimal Vitamin D Serum Levels
Keeping a beneficial serum level at all times is extremely important. Studies show that 40ng/ml is the minimum needed foe cancer prevention. According to a 2009 study,
“Higher serum levels of the main circulating form of vitamin D, 25-hydroxyvitamin D (25(OH)D), are associated with substantially lower incidence rates of colon, breast, ovarian, renal, pancreatic, aggressive prostate and other cancers. Epidemiological findings combined with newly discovered mechanisms suggest a new model of cancer etiology that accounts for these actions of 25(OH)D and calcium. Its seven phases are disjunction, initiation, natural selection, overgrowth, metastasis, involution, and transition (abbreviated DINOMIT). Vitamin D metabolites prevent disjunction of cells and are beneficial in other phases.
It is projected that raising the minimum year-around serum 25(OH)D level to 40 to 60 ng/mL (100–150 nmol/L) would prevent approximately 58,000 new cases of breast cancer and 49,000 new cases of colorectal cancer each year, and three fourths of deaths from these diseases in the United States and Canada, based on observational studies combined with a randomized trial.
Such intakes also are expected to reduce case-fatality rates of patients who have breast, colorectal, or prostate cancer by half… The time has arrived for nationally coordinated action to substantially increase intake of vitamin D and calcium.”
Last but not least, it is important to provide general supplementation guidelines. A research by GrassrootsHealth suggests that adult individuals need 8,000 IUs daily to reach a serum level of 40 ng/ml, which is considered a healthy serum level. With this being said it is recommended to increase your sun exposure and wisely choose your supplements to boost your vitamin D levels.